New screening method finds rare DNA gyrase poison for future antibiotics
Phys.org ·
The goal was to build a faster way to search for new antibiotics. The search turned up something unexpected. FIU biochemistry professor Fenfei Leng and a group of researchers set out to develop the first high-throughput screening method specifically designed to identify compounds that can poison bacterial DNA gyrase, an enzyme that bacteria need to survive.
The goal was to build a faster way to search for new antibiotics. The search turned up something unexpected. FIU biochemistry professor Fenfei Leng and a group of researchers set out to develop the first high-throughput screening method specifically designed to identify compounds that can poison bacterial DNA gyrase, an enzyme that bacteria need to survive.