Underlying mechanism of Atg2-mediated lipid transfer in autophagy identified
Phys.org ·
Autophagy is an intracellular degradation mechanism in eukaryotes. The autophagosome, which encloses damaged or excess cellular material for degradation, is constructed from lipids supplied by the endoplasmic reticulum (ER) via the lipid transfer protein Atg2.
Autophagy is an intracellular degradation mechanism in eukaryotes. The autophagosome, which encloses damaged or excess cellular material for degradation, is constructed from lipids supplied by the endoplasmic reticulum (ER) via the lipid transfer protein Atg2.